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01 Jul 2024 - 06:45 am
Common low-calorie sweetener linked to heart attack and stroke, study finds
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A low-calorie sweetener called xylitol used in many reduced-sugar foods and consumer products such as gum and toothpaste may be linked to nearly twice the risk of heart attacks, stroke and death in people who consume the highest levels of the sweetener, a new study found.
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“We gave healthy volunteers a typical drink with xylitol to see how high the levels would get and they went up 1,000-fold,” said senior study author Dr. Stanley Hazen, director of the Center for Cardiovascular Diagnostics and Prevention at the Cleveland Clinic Lerner Research Institute.
“When you eat sugar, your glucose level may go up 10% or 20% but it doesn’t go up a 1,000-fold,” said Hazen, who also directs the Cleveland Clinic’s Center for Microbiome and Human Health.
“Humankind has not experienced levels of xylitol this high except within the last couple of decades when we began ingesting completely contrived and sugar-substituted processed foods,” he added.
Worrisome blood clots occur
In 2023, the same researchers found similar results for another low-calorie sweetener called erythritol, which is used as a bulking sugar in stevia, monkfruit and keto reduced-sugar products.
Additional lab and animal research presented in both papers revealed erythritol and xylitol may cause blood platelets to clot more readily. Clots can break off and travel to the heart, triggering a heart attack, or to the brain, triggering a stroke.
In the new study on xylitol, “differences in platelet behavior were seen even after a person consumed a modest quantity of xylitol in a drink typical of a portion consumed in real life,” said Dr. Matthew Tomey, a cardiologist at Mount Sinai Fuster Heart Hospital in New York City, who was not involved in the study.
“These experiments are interesting but alone do not prove that platelet abnormalities are to account for a linkage between xylitol and clinical events,” said Tomey, who is also an assistant professor of medicine at the Icahn School of Medicine at Mount Sinai.
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01 Jul 2024 - 05:50 am
‘Sugary food is a drug for me’: A growing number of children are addicted to ultraprocessed foods
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Chicago native Jeffrey Odwazny says he has been addicted to ultraprocessed food since he was a child.
“I was driven to eat and eat and eat, and while I would overeat healthy food, what really got me were the candies, the cakes, the pies, the ice cream,” said the 54-year-old former warehouse supervisor
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“I really gravitated towards the sugary ultraprocessed foods — it was like a physical drive, I had to have it,” he said. “My parents would find hefty bags full of candy wrappers hidden in my closet. I would steal things from stores as a kid and later as an adult.”
Some 12% of the nearly 73 million children and adolescents in the United States today struggle with a similar food addiction, according to research. To be diagnosed, children must meet Yale Food Addiction Scale criteria as stringent as any for alcohol use disorder or other addictions.
“Kids are losing control and eating to the point where they feel physically ill,” said Ashley Gearhardt, a professor of psychology at the University of Michigan in Ann Arbor who conducted the research and developed the Yale addiction scale.
“They have intense cravings and may be sneaking, stealing or hiding ultraprocessed foods,” Gearhardt said. “They may stop going out with friends or doing other activities they used to enjoy in order to stay at home and eat, or they feel too sluggish from overeating to participate in other activities.”
Her research also shows about 14% of adults are clinically addicted to food, predominantly ultraprocessed foods with higher levels of sugar, salt, fat and additives.
For comparison, 10.5% of Americans age 12 or older were diagnosed with alcohol use disorder in 2022, according to the National Survey on Drug Use and Health.
While many people addicted to food will say that their symptoms began to worsen significantly in adolescence, some recall a childhood focused on ultraprocessed food.
“By age 2 or 3, children are likely eating more ultraprocessed foods in any given day than a fruit or vegetable, especially if they’re poor and don’t have enough money in their family to have enough quality food to eat,” Gearhardt said. “Ultraprocessed foods are cheap and literally everywhere, so this is also a social justice issue.”
An addiction to ultraprocessed foods can highjack a young brain’s reward circuitry, putting the primitive “reptilian brain,” or amygdala, in charge — thus bypassing the prefrontal cortex where rational decision-making occurs, said Los Angeles registered dietitian nutritionist David Wiss, who specializes in treating food addiction.
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